Method for inducing human blood-born hematospheres through aggregate culture and expanding blood adult stem cells and progenitor cells, and stem cell prepared by the same

US8969079B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8969079-B2
Application numberUS-201113819409-A
CountryUS
Kind codeB2
Filing dateAug 8, 2011
Priority dateAug 27, 2010
Publication dateMar 3, 2015
Grant dateMar 3, 2015

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Abstract

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The present invention relates to a technique of using monocytic blood cells to effectively culture and proliferate blood adult stem cells and progenitor cells that only exist in small quantities to effectively obtain large quantities of stem cells. According to the present invention, the limitation of being able to derive only small quantities of stem cells from blood can be overcome, and the pluripotency of stem cells can easily be obtained.

First claim

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We claim: 1. A method for proliferating blood adult stem cells using human blood-born hematospheres, comprising: isolating mononuclear cells from blood; aggregate culturing the isolated cells in a three-dimensional structure; proliferating the three-dimensionally cultured cells to form blood-born hematospheres; and dissociating the blood-born hematospheres into single cells; wherein the blood adult stem cells are contained and proliferated within the blood-born hematospher…

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What does patent US8969079B2 cover?
The present invention relates to a technique of using monocytic blood cells to effectively culture and proliferate blood adult stem cells and progenitor cells that only exist in small quantities to effectively obtain large quantities of stem cells. According to the present invention, the limitation of being able to derive only small quantities of stem cells from blood can be overcome, and the p…
Who is the assignee on this patent?
Park Young-Bae, Kim Hyo-Soo, Kang Hyun-Jae, and 4 more
What technology area does this patent fall under?
Primary CPC classification C12N5/0647. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).