Method of detaching adherent cells for flow cytometry
US-2015368620-A1 · Dec 24, 2015 · US
Method for a rational cell culturing process
US8969043B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8969043-B2 |
| Application number | US-201013321877-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 27, 2010 |
| Priority date | May 28, 2009 |
| Publication date | Mar 3, 2015 |
| Grant date | Mar 3, 2015 |
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Abstract
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Biopharmaceutical process development with recombinant protein producing mammalian cells has realized a tremendous increase in both productivity and product yields in the past years. These achievements can be mainly attributed to the advancements in cell line development, media, and process optimization. Only recently, genome-scale technologies enable a system-level analysis to elucidate the complex biomolecular basis of protein production in mammalian cells promising an increased process understanding and the deduction of knowledge-based approaches for further process optimization. The present invention describes a method for a rational cell culturing process using such a knowledge-based approach.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for producing a product of interest comprising a) providing a mammalian host cell, b) culturing said cell according to a process A, c) culturing said cell according to a process B, which is different from process A, d) employing a comparative method suitable to distinguish between the different performance levels of said cell in process A versus process B, e) identifying biological functions and pathways which relate to the two differe…
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- G01N33/5005Primary
Physics · mapped topic
Physics · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US8969043B2 cover?
- Biopharmaceutical process development with recombinant protein producing mammalian cells has realized a tremendous increase in both productivity and product yields in the past years. These achievements can be mainly attributed to the advancements in cell line development, media, and process optimization. Only recently, genome-scale technologies enable a system-level analysis to elucidate the co…
- Who is the assignee on this patent?
- Schaub Jochen, Schulz Torsten, Boehringer Ingelheim Int
- What technology area does this patent fall under?
- Primary CPC classification G01N33/5005. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).