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US-2024369481-A1 · Nov 7, 2024 · US
US8965737B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8965737-B2 |
| Application number | US-201113284025-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 28, 2011 |
| Priority date | Oct 28, 2011 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Official abstract text for this publication.
A device, including sample and reference channels through which first and second solutions flow, respectively, the first solution including an analyte, the channels having a metal film in contact with the first and second solutions, the metal film configured with a linker to selectively bind the analyte; a light source whose output is modulated by an optical system, so that light is directed from the optical system alternately towards the sample and reference channels, surface plasmons within the metal film being created; a first photodetector that monitors the strength of the output from the light source; a second photodetector that collects optical signals reflected from the metal film; electronics that monitors output from the first and the second photodetectors, thereby detecting a noise-compensated difference in signals from the two channels; and a computer processor that determines, from analysis of the noise-compensated difference, presence of the analyte in the first solution.
Opening claim text (preview).
What is claimed is: 1. A device, comprising: sample and reference channels through which first and second solutions flow, respectively, wherein the first solution includes an analyte of interest, the channels having a metal film in contact with the first and second solutions, a surface of the metal film configured with a linker to selectively bind the analyte to the surface of the metal film; a light source whose output is modulated by an optical system, so that light is directe…
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
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