Immunomodulator compounds
US-2018008554-A1 · Jan 11, 2018 · US
US8962891B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962891-B2 |
| Application number | US-74204508-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 9, 2008 |
| Priority date | Nov 8, 2007 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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The present invention provides new ceramide analogs indicated as the compounds of formula (II). These novel analogs exhibit a significant anti cancerous effect and are therefore provided as a pharmaceutical composition for treating cell proliferative diseases, neurodegenerative disorders, metabolism-associated conditions, infectious diseases, and immune-related disorders. The invention further provides combined compositions and kits combining the novel ceramide analogs of formula (II) with an additional therapeutic agent.
Opening claim text (preview).
The invention claimed is: 1. A method for the treatment of a proliferative disorder comprising administering to a subject a therapeutically effective amount of compound of formula (II): wherein X represents a hydrogen atom or OH; Y represents —NHR 6 , wherein R 6 represents a C 2-20 linear or branched alkyl or unsubstituted alkenyl chain or alkenyl chain t…
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