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Process for synthesizing keto benzofuran derivatives
US8962869B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962869-B2 |
| Application number | US-201214006027-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 23, 2012 |
| Priority date | Mar 24, 2011 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
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The invention relates to a method for synthesizing benzofuran derivatives, in particular the dronedarone of formula (D), including carrying out a Fries rearrangement reaction using a sulfonamido-benzofuran ester intermediate.
First claim
Opening claim text (preview).
The invention claimed is: 1. A process for synthesizing a keto benzofuran derivative, in acid form (i), in base form (ii), in the form of an addition salt with an acid or a base (iii), in hydrate form (iv) or in solvate form (v), advantageously dronedarone or the hydrochloride salt thereof, said keto benzofuran derivative being of formula (I) below: in which G1 represents a lin…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
- C07D307/84Primary
Chemistry & Metallurgy · mapped topic
- C07D307/80Primary
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8962869B2 cover?
- The invention relates to a method for synthesizing benzofuran derivatives, in particular the dronedarone of formula (D), including carrying out a Fries rearrangement reaction using a sulfonamido-benzofuran ester intermediate.
- Who is the assignee on this patent?
- Grimaud Bernard, Grossi Pierre-Jean, Sanofi Sa
- What technology area does this patent fall under?
- Primary CPC classification C07D307/84. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).