Hepatitis b antiviral agents
US-2017334882-A1 · Nov 23, 2017 · US
Methods and compounds useful in the synthesis of fused aminodihydrothiazine derivatives
US8962858B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962858-B2 |
| Application number | US-201414316321-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 26, 2014 |
| Priority date | Jan 21, 2011 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
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Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.
First claim
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We claim: 1. A compound of Formula I: wherein: R 1 is halo-C 1-4 alkyl, hydroxy-C 1-4 alkyl, or —C 1-4 alkyl-OR′, wherein R′ is an oxygen protecting group; and R 2 and R 3 are each independently hydrogen or halo; subject to the proviso that when one of R 2 or R 3 is ortho-fluoro, and the other is hydrogen, R 1 is not —CH 2 F; and wh…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
- C07D307/22Primary
Chemistry & Metallurgy · mapped topic
- C07D498/04Primary
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8962858B2 cover?
- Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.
- Who is the assignee on this patent?
- Eisai R&D Man Co Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07D307/22. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).