Difluorocarbene radiosynthesis
US-2024383827-A1 · Nov 21, 2024 · US
US8962848B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962848-B2 |
| Application number | US-201414173338-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 5, 2014 |
| Priority date | Mar 12, 2010 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Disclosed is a compound containing a pyridine ring that can be synthesized in an industrially advantageous manner, and is useful as an intermediate for producing tetrazolyloxime derivatives that exhibit fungicidal activity (wherein R 0 represents a C 1-6 alkoxy group, C 1-6 alkoxy-C 1-6 alkoxy group or the like, R 1 represents a C 1-2 alkoxycarbonyl group, acetyl group or the like, Z represents a halogen atom, cyano group or the like, X represents a halogen atom, and n represents an integer of 0 to 3), and industrially advantageous production methods for producing 2-substituted amino-6-halomethylpyridine derivatives and tetrazolyloxime derivatives.
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The invention claimed is: 1. A method for producing a brominated picoline derivative represented by formula (6), the method comprising reacting a brominated picoline derivative represented by formula (4) and/or formula (5), a phosphite ester, and a base in an organic solvent, wherein R 1b represents an unsubstituted or substituent-containing alkoxycarbonyl group, R 2b…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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