Salts of raltegravir

US8962833B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8962833-B2
Application numberUS-201013699368-A
CountryUS
Kind codeB2
Filing dateMay 25, 2010
Priority dateMay 25, 2010
Publication dateFeb 24, 2015
Grant dateFeb 24, 2015

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Abstract

Official abstract text for this publication.

The present invention provides novel salts of raltegravir, processes for their preparation and pharmaceutical compositions comprising them. The present invention also provides crystalline sodium salt of raltegravir, process for its preparation and pharmaceutical compositions comprising it. The present invention further provides a process for the preparation of amorphous sodium salt of raltegravir. The present invention further provides a process for the preparation of raltegravir potassium crystalline form H1.

First claim

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We claim: 1. A process for the preparation of raltegravir potassium crystalline form H1, comprising: a. suspending raltegravir in an non-aqueous alcoholic solvent to provide a suspension; b. adding potassium hydroxide to the suspension obtained in step (a) to provide a reaction mass; c. stirring the reaction mass obtained in step (b) at about 25 to 30° C. to provide a slurry, wherein stirring is for a time sufficient to produce raltegravir potassium crystalline form H1 and whe…

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What does patent US8962833B2 cover?
The present invention provides novel salts of raltegravir, processes for their preparation and pharmaceutical compositions comprising them. The present invention also provides crystalline sodium salt of raltegravir, process for its preparation and pharmaceutical compositions comprising it. The present invention further provides a process for the preparation of amorphous sodium salt of raltegrav…
Who is the assignee on this patent?
Reddy Bandi Parthasaradhi, Reddy Kura Rathnakar, Reddy Dasari Muralidhara, and 4 more
What technology area does this patent fall under?
Primary CPC classification C07D413/12. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).