2,6-dihalo-5-alkoxy-4-substituted-pyrimidines, pyrimidine-carbaldehydes, and methods of formation and use
US-9216958-B2 · Dec 22, 2015 · US
Process for the preparation of ambrisentan and novel intermediates thereof
US8962832B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962832-B2 |
| Application number | US-201013382988-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 12, 2010 |
| Priority date | Jul 10, 2009 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
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The invention relates to improved processes for the preparation of ambrisentan. The invention also relates to a novel intermediate useful in the preparation of ambrisentan and a process for the preparation of the intermediate. The invention also relates to new polymorphic form of ambrisentan. In particular, it relates to a polymorphic form, designated as Form I of ambrisentan and a process for the preparation of the Form I.
First claim
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The invention claimed is: 1. A process for preparing Ambrisentan of formula (I), the process comprising: a) resolving racemic 2-hydroxy propanoic acid of formula (VIII), with chiral amine of formula (IX),…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
- C07D239/34Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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- What does patent US8962832B2 cover?
- The invention relates to improved processes for the preparation of ambrisentan. The invention also relates to a novel intermediate useful in the preparation of ambrisentan and a process for the preparation of the intermediate. The invention also relates to new polymorphic form of ambrisentan. In particular, it relates to a polymorphic form, designated as Form I of ambrisentan and a process for …
- Who is the assignee on this patent?
- Sata Kaushik Babubhai, Pandey Bipin, Cadila Healthcare Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07D239/34. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).