Modified cytomegalovirus proteins and stabilized complexes
US-2024383949-A1 · Nov 21, 2024 · US
Constructs for enhancing immune responses
US8962816B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962816-B2 |
| Application number | US-201113239771-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 22, 2011 |
| Priority date | Aug 28, 2006 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
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Chimeric protein constructs including a herpesvirus glycoprotein D (gD) and a heterologous polypeptide that interact with herpes virus entry mediator (HVEM) and enhance and enhance an immune response against the heterologous polypeptide and methods for their use are provided.
First claim
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The invention claimed is: 1. A nucleic acid molecule which encodes a fusion protein, wherein the fusion protein comprises: (1) a first polypeptide segment comprising at least amino acids 1-240 of a mature Herpes simplex virus (HSV) glycoprotein D, wherein the first polypeptide segment does not comprise a full length mature glycoprotein D; (2) a second polypeptide segment comprising at least one antigen, wherein the at least one antigen is not an HSV glycoprotein D antigen, where…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US8962816B2 cover?
- Chimeric protein constructs including a herpesvirus glycoprotein D (gD) and a heterologous polypeptide that interact with herpes virus entry mediator (HVEM) and enhance and enhance an immune response against the heterologous polypeptide and methods for their use are provided.
- Who is the assignee on this patent?
- Ertl Hildegund C J, Lasaro Marcio O, Ferreira Luis C S, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification A61K39/245. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).