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Fluorescent probe compounds, preparation method and application thereof
US8962339B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962339-B2 |
| Application number | US-201013521047-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 6, 2010 |
| Priority date | Jan 15, 2010 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
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The present invention discloses a fluorescent probe compound which solved the problem of fluorescence quenching by Pd 2+ , and its preparation method and use as well. Excitation and emission wavelengths of the probe compound are in visible light region. The probe compound is highly sensitive and displays good selectivity for Pd 2+ in near-neutral pH range. In detection of Pd 2+ in 0-10 ppb level, fluorescence is evidently enhanced, and Pd 2+ in the level as low as 5 nM can be detected. Fluorescence intensity is well linearly correlated to Pd 2+ concentration. The probe compound can be used for detection of contaminating palladium and residual palladium in drug, soil, water sample and reactor.
First claim
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The invention claimed is: 1. A fluorescence probe compound of general formula I: wherein R 1 , R 2 , R 3 and R 4 are each independently selected from the group consisting of H, C 1-6 alkyl, C 1-6 alkyl substituted phenyl, C 1-6 alkyl substituted naphthyl, halogen, OR 8 , N(R 8 ) 2 , CN, (CH 2 CH 2 O) n H, (CH 2 ) m COOM and (CH 2 ) m SO 3 M; R 5 , R 6…
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Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
- C07F9/6561Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US8962339B2 cover?
- The present invention discloses a fluorescent probe compound which solved the problem of fluorescence quenching by Pd 2+ , and its preparation method and use as well. Excitation and emission wavelengths of the probe compound are in visible light region. The probe compound is highly sensitive and displays good selectivity for Pd 2+ in near-neutral pH range. In detection of Pd 2+ in 0-10 ppb le…
- Who is the assignee on this patent?
- Peng Xiaojun, Fan Jiangli, Li Honglin, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C07F9/6561. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).