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Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor
US8962332B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962332-B2 |
| Application number | US-201314025951-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 13, 2013 |
| Priority date | Dec 17, 2001 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
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Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles.
First claim
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The invention claimed is: 1. A composition comprising a non-naturally occurring recombinant adeno-associated virus (AAV) comprising an AAV8 capsid comprising a vp1, vp2, and a vp3 protein, wherein said vp1 protein has an amino acid sequence which is at least about 95% identical to amino acids 1 to 737 of SEQ ID NO: 2, said composition further comprising a pharmaceutically acceptable carrier. 2. The composition according to claim 1 , wherein said vp1 protein has…
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Frequently asked questions
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- What does patent US8962332B2 cover?
- Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles.
- Who is the assignee on this patent?
- Univ Pennsylvania
- What technology area does this patent fall under?
- Primary CPC classification C12N15/86. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).