Enzymes for producing non-straight-chain fatty acids
US-2015376659-A1 · Dec 31, 2015 · US
Four-gene pathway for wax ester synthesis
US8962299B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962299-B2 |
| Application number | US-201213408270-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 29, 2012 |
| Priority date | Feb 29, 2012 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
Official abstract text for this publication.
The invention relates to methods for producing a wax ester in recombinant host cells engineered to express a thioesterase, an acyl-CoA synthetase, an alcohol-forming fatty acyl reductase, and a wax ester synthase. The methods of the invention may take place in photosynthetic microorganisms, and particularly in cyanobacteria. Isolated nucleotide molecules and vectors expressing the thioesterase, acyl-CoA synthetase, alcohol-forming fatty acyl reductase, and wax ester synthase, recombinant host cells expressing the thioesterase, acyl-CoA synthetase, alcohol-forming fatty acyl reductase, and wax ester synthase, and systems for producing a wax ester via a pathway using these four enzymes, are also provided.
First claim
Opening claim text (preview).
What is claimed is: 1. A nucleic acid molecule comprising: a) a nucleic acid sequence encoding a thioesterase belonging to Pfam PF01643 or PF02551; b) a nucleic acid sequence encoding an acyl-CoA synthetase; c) a nucleic acid sequence encoding an alcohol-forming fatty acyl-CoA reductase selected from the group consisting of amino acid sequences having at least 85% sequence identity to any one of SEQ ID NOs:15-21; and d) a nucleic acid sequence encoding a wax ester synthase b…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12P7/6436Primary
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8962299B2 cover?
- The invention relates to methods for producing a wax ester in recombinant host cells engineered to express a thioesterase, an acyl-CoA synthetase, an alcohol-forming fatty acyl reductase, and a wax ester synthase. The methods of the invention may take place in photosynthetic microorganisms, and particularly in cyanobacteria. Isolated nucleotide molecules and vectors expressing the thioesterase,…
- Who is the assignee on this patent?
- Holtzapple Erik, Verruto John H, Exxonmobil Res & Eng Co
- What technology area does this patent fall under?
- Primary CPC classification C12P7/6436. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).