Systems and methods for measuring cell signaling protein activity
US-2024230643-A9 · Jul 11, 2024 · US
US8962298B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962298-B2 |
| Application number | US-74191607-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 30, 2007 |
| Priority date | May 2, 2006 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein.
Opening claim text (preview).
What is claimed is: 1. A recombinant microbial host cell comprising heterologous DNA molecules encoding polypeptides that catalyze the substrate to product conversions below: i) pyruvate to alpha acetolactate; ii) alpha acetolactate to acetoin; iii) acetoin to 2,3-butanediol; and iv) 2,3-butanediol to 2-butanone; wherein said microbial host cell produces 2-butanol; and wherein the polypeptide that catalyzes the substrate to product conversion of 2,3-butanediol to 2-butan…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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