Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
US-9222112-B2 · Dec 29, 2015 · US
US8962276B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962276-B2 |
| Application number | US-201213646667-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 6, 2012 |
| Priority date | Oct 6, 2012 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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The present invention provides novel fatty acid desaturases genes used for synthesis of polyunsaturated fatty acids, especially omega-3 desaturases (FADS15). The present invention also provides nucleic acid sequence coding the above-described desaturases, expression vector of the above-described desaturases and recombinant microorganism expressing above-described desaturases.
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The invention claimed is: 1. A vector comprises a cDNA molecule having the nucleotide sequence shown as SEQ ID NO:1, wherein said cDNA is cloned into pPinkα-HC vector that expresses a secreted omega-3 desaturase having the amino acid sequence shown as SEQ ID NO:2. 2. The vector according to claim 1 , said vector is able to be utilized for treatment of fatty acid-associated disorders in a subject. 3. The vector according to claim 2 , said su…
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