Ash1l degraders and methods of treatment therewith
US-2024366774-A1 · Nov 7, 2024 · US
US8961981B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8961981-B2 |
| Application number | US-201213527142-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 19, 2012 |
| Priority date | Jun 20, 2011 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Compositions and methods for targeting therapeutic agents to neuromuscular junctions are disclosed. Also disclosed are methods for treating diseases and conditions affecting the neuromuscular junction. Compositions include a neuromuscular junction targeting peptide coupled to a therapeutic agent. Compositions may further include a linker peptide. Methods for targeting therapeutic agents to neuromuscular junctions and treating diseases and conditions affecting the neuromuscular junction include administering a composition including a neuromuscular junction targeting peptide coupled to a therapeutic agent.
Opening claim text (preview).
What is claimed is: 1. A composition comprising a neuromuscular junction targeting peptide coupled to a therapeutic agent, wherein the neuromuscular junction targeting peptide is selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 9 and wherein the therapeutic agent is selected from the group consisting of a complement inhibitor, an acetylcholinesterase inhibitor, and a trophic agent. 2. The composition of claim 1 , wh…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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