Targeting the neuromuscular junction for treatment

US8961981B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8961981-B2
Application numberUS-201213527142-A
CountryUS
Kind codeB2
Filing dateJun 19, 2012
Priority dateJun 20, 2011
Publication dateFeb 24, 2015
Grant dateFeb 24, 2015

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  2. Abstract

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  3. Assignees and inventors

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  5. First independent claim

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Abstract

Official abstract text for this publication.

Compositions and methods for targeting therapeutic agents to neuromuscular junctions are disclosed. Also disclosed are methods for treating diseases and conditions affecting the neuromuscular junction. Compositions include a neuromuscular junction targeting peptide coupled to a therapeutic agent. Compositions may further include a linker peptide. Methods for targeting therapeutic agents to neuromuscular junctions and treating diseases and conditions affecting the neuromuscular junction include administering a composition including a neuromuscular junction targeting peptide coupled to a therapeutic agent.

First claim

Opening claim text (preview).

What is claimed is: 1. A composition comprising a neuromuscular junction targeting peptide coupled to a therapeutic agent, wherein the neuromuscular junction targeting peptide is selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 9 and wherein the therapeutic agent is selected from the group consisting of a complement inhibitor, an acetylcholinesterase inhibitor, and a trophic agent. 2. The composition of claim 1 , wh…

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What does patent US8961981B2 cover?
Compositions and methods for targeting therapeutic agents to neuromuscular junctions are disclosed. Also disclosed are methods for treating diseases and conditions affecting the neuromuscular junction. Compositions include a neuromuscular junction targeting peptide coupled to a therapeutic agent. Compositions may further include a linker peptide. Methods for targeting therapeutic agents to neur…
Who is the assignee on this patent?
Kaminski Henry, Kusner Linda, Satija Namita, and 1 more
What technology area does this patent fall under?
Primary CPC classification A61K47/64. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).