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Method for assessment of hepatic function and portal blood flow
US8961925B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8961925-B2 |
| Application number | US-201213484083-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 30, 2012 |
| Priority date | May 31, 2011 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
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A method for estimating portal blood flow and hepatic function in a subject is provided. In one example, the STAT test is an in vitro simplified, convenient test intended for screening purposes that can reasonably estimate the portal blood flow from a single blood sample taken 60 minutes after orally administered deuterated-cholate. The test can be administered to a patient having, or suspected of having, Chronic Hepatitis C, Primary Sclerosing Cholangitis (PSC), Non-Alcoholic Fatty Liver Disease (NAFLD), or any chronic liver disease.
First claim
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We claim: 1. An in vitro method for estimation of portal blood flow in a subject, the method comprising: receiving a blood or serum sample consisting of a single sample collected from a subject suspected of having or developing, a hepatic disorder at a single, specific time point within 3 hours after oral administration of a stable isotope labeled distinguishable cholate compound to the subject, wherein no other distinguishable cholate compound is intravenously co-administered;…
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- What does patent US8961925B2 cover?
- A method for estimating portal blood flow and hepatic function in a subject is provided. In one example, the STAT test is an in vitro simplified, convenient test intended for screening purposes that can reasonably estimate the portal blood flow from a single blood sample taken 60 minutes after orally administered deuterated-cholate. The test can be administered to a patient having, or suspected…
- Who is the assignee on this patent?
- Everson Gregory Thomas, Helmke Steve Mark, Univ Colorado Regents
- What technology area does this patent fall under?
- Primary CPC classification G01N33/92. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).