Phrenic nerve stimulation
US-2024173074-A1 · May 30, 2024 · US
US8958879B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8958879-B2 |
| Application number | US-201414273917-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 9, 2014 |
| Priority date | Aug 3, 2009 |
| Publication date | Feb 17, 2015 |
| Grant date | Feb 17, 2015 |
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Embodiments of the invention provide apparatus and methods for stimulating L cells in the intestinal tract to produce incretins for the treatment of conditions including diabetes and obesity. Many embodiments provide a method and apparatus for the treatment of diabetes by electrically stimulating L-cells to secrete incretins to stimulate or otherwise modulate the production of insulin. Particular embodiments provide a swallowable capsule for stimulating L-cells in the intestinal tract as the capsule moves through the tract. The capsule can include two or more electrodes for providing electrical stimulation to L-cells, a power source for powering one or more components of the capsule, a sensor for sensing the location of the capsule in the intestinal tract; a controller and a waveform generator for generating the electrical signals emitted by the electrodes to stimulate the L-cells to secrete incretins such as GLP-1 to stimulate insulin production for glucose regulation of diabetic conditions.
Opening claim text (preview).
What is claimed is: 1. A method for stimulating incretin-producing cells (IP-cells) in the intestinal tract of a patient to secrete an incretin, the method comprising: ingesting a swallowable device configured to travel through the intestinal tract and electrically stimulate the IP-cells at any location in the intestinal tract; delivering an electrical signal from the device to an intestinal wall proximate the device, wherein the signal includes a waveform configured to electric…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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