Cyclohexyl beta-hydroxy alkyl amines and medical uses thereof
US-2024390298-A1 · Nov 28, 2024 · US
US8957205B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8957205-B2 |
| Application number | US-8761707-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 10, 2007 |
| Priority date | Jan 11, 2006 |
| Publication date | Feb 17, 2015 |
| Grant date | Feb 17, 2015 |
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Novel cycloalkane carboxamide derivatives having an action that selectively inhibits cathepsin K, and a production process thereof, are provided, wherein the cycloalkane carboxamide derivatives are represented by the following general formula (I), or a pharmaceutically acceptable salt thereof: (wherein R 1 and R 2 represent (substituted) alkyl groups, (substituted) alkenyl groups, (substituted) alkynyl groups, (substituted) aromatic hydrocarbon groups or (substituted) heterocyclic groups, ring A represents an alkylidene group having 5 to 7 carbon atoms, and ring B represents a formyl group or a hydroxymethyl group).
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The invention claimed is: 1. A cycloalkane carboxamide compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R 1 is a substituted or unsubstituted monocyclic or polycyclic C 6-18 aromatic hydrocarbon group or a substituted or unsubstituted 3- to 7-membered heterocyclic ring group containing at least one nitrogen atom, oxygen atom or sulfur atom as a…
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