Sensitization of tumor cells to radiation therapy through administration of endothelin agonists

US8957014B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8957014-B2
Application numberUS-201313761043-A
CountryUS
Kind codeB2
Filing dateFeb 6, 2013
Priority dateOct 24, 2002
Publication dateFeb 17, 2015
Grant dateFeb 17, 2015

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Abstract

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Methods to sensitize tumor cells to radiation therapy through the administration of an endothelin agonist such as the ET B agonist IRL1620.

First claim

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The invention claimed is: 1. A radiation combination therapy contributing to the treatment of a lymphoma in a patient in need thereof, the therapy comprising administering a first radiation sensitizing compound and a second radiation sensitizing compound to the patient, wherein administration of the first radiation sensitizing compound increases oxygenation of the lymphoma, thereby sensitizing the lymphoma to radiation-induced cellular damage, and wherein the first radiation sensi…

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What does patent US8957014B2 cover?
Methods to sensitize tumor cells to radiation therapy through the administration of an endothelin agonist such as the ET B agonist IRL1620.
Who is the assignee on this patent?
Univ Illinois, Spectrum Pharmaceuticals Inc, Trustees Of The University Of Illinoise Board Of
What technology area does this patent fall under?
Primary CPC classification A61K41/0038. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).