Atherosclerosis-targeted liposome nanocarrier delivery system and preparation method therefor
US-2024424132-A1 · Dec 26, 2024 · US
Gamma secretase inhibitor for treatment of herpesvirus infection
US8957012B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8957012-B2 |
| Application number | US-201213357452-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 24, 2012 |
| Priority date | Jul 5, 2006 |
| Publication date | Feb 17, 2015 |
| Grant date | Feb 17, 2015 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
This invention relates to methods and compositions for the treatment of malignancies associated with gamma-herpesvirus infection. Specifically, the invention relates to the use of gamma-secretase inhibitors to prevent the production of intracellular Notch1 thereby arresting the growth of the infected cells.
First claim
Opening claim text (preview).
What is claimed is: 1. A method for treating a virus-induced lymphoproliferative disease, the method, comprising: the step of administering to a subject in need thereof a therapeutically effective amount of a γ-secretase inhibitor. 2. The method of claim 1 , wherein the virus is an Epstein-Barr virus (EBV) or a human herpesvirus 8 (HHV8). 3. The method of claim 1 , wherein the virus is a γ-herpesvirus. 4. The method of…
Assignees
Inventors
Classifications
- A61K31/195Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Patent family
Related publications grouped by family.
External sources
Next steps
Free tools are coming soon. Tell us what you want to track and we'll notify you.
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US8957012B2 cover?
- This invention relates to methods and compositions for the treatment of malignancies associated with gamma-herpesvirus infection. Specifically, the invention relates to the use of gamma-secretase inhibitors to prevent the production of intracellular Notch1 thereby arresting the growth of the infected cells.
- Who is the assignee on this patent?
- Robertson Erle S, Lan Ke, Univ Pennsylvania
- What technology area does this patent fall under?
- Primary CPC classification A61K31/195. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).