Glyconjugate Vaccines
US-2024382585-A1 · Nov 21, 2024 · US
US8956830B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8956830-B2 |
| Application number | US-201313829292-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 14, 2013 |
| Priority date | Mar 14, 2013 |
| Publication date | Feb 17, 2015 |
| Grant date | Feb 17, 2015 |
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Polypeptide preparations having target levels of glycans, and methods of producing such polypeptide preparations using DMSO, are described.
Opening claim text (preview).
The invention claimed is: 1. A method of producing a recombinant protein preparation having target values of high mannose glycans and fucosylated glycans, the method comprising: (a) providing a mammalian cell genetically engineered to express a recombinant protein; (b) culturing the cell in a culture medium comprising dimethylsulfoxide (DMSO) under conditions in which the cell expresses the recombinant protein; and (c) harvesting a preparation of the recombinant protein produc…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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