Aryl and heteroaryl ether compounds as ROR gamma modulators
US-9718817-B2 · Aug 1, 2017 · US
Phosphorylated and branched dihydroxy-pentane-dione (DPD) analogs as quorum sensing inhibitors in bacteria
US8952192B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8952192-B2 |
| Application number | US-201213430000-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 26, 2012 |
| Priority date | Mar 24, 2011 |
| Publication date | Feb 10, 2015 |
| Grant date | Feb 10, 2015 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Provided are compositions and methods for modulating quorum sensing in microbes. The compounds are AI-2 analogs and as such have structures similar to 4,5-dihydroxy-2,3-pentanedione that can act as agonists/antagonists of quorum sensing. The compounds are useful for modulating quorum sensing in bacteria and can be used in methods for prophylaxis or therapy of bacterial infections and for reduction of biofilms.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound having the following structure: wherein R and R 3 are each are each independently a phosphonate group, sulfonate group, sulfoxide group, or carboxylate group, ii) R is a phosphonate group, sulfonate group, sulfoxide group, or carboxylate group and R 3 is a H or keto group, or iii) R 3 is a phosphonate group, sulfonate group, sulfoxide group,…
Assignees
Inventors
Classifications
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Patent family
Related publications grouped by family.
External sources
Next steps
Free tools are coming soon. Tell us what you want to track and we'll notify you.
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US8952192B2 cover?
- Provided are compositions and methods for modulating quorum sensing in microbes. The compounds are AI-2 analogs and as such have structures similar to 4,5-dihydroxy-2,3-pentanedione that can act as agonists/antagonists of quorum sensing. The compounds are useful for modulating quorum sensing in bacteria and can be used in methods for prophylaxis or therapy of bacterial infections and for reduct…
- Who is the assignee on this patent?
- Sintim Herman O, Bentley William E, Roy Varnika, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C07C317/24. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).