Conjugates, preparation thereof, and therapeutic use thereof

US8952147B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8952147-B2
Application numberUS-201113331259-A
CountryUS
Kind codeB2
Filing dateDec 20, 2011
Priority dateJun 29, 2009
Publication dateFeb 10, 2015
Grant dateFeb 10, 2015

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

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Provided herein are cryptophycin conjugates and compositions containing them. Methods of making and using such compounds also are provided.

First claim

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We claim: 1. A compound of formula (II): in which: R 1 represents a halogen atom and R 2 represents an —OH, an acyl group derived from an amino acid AA, or a (C 1 -C 4 )alkanoyloxy group or alternatively R 1 and R 2 form an epoxide unit; AA denotes a natural or unnatural amino acid; R 3 represents a (C 1 -C 6 )alkyl group; R 4 and R 5 both represent H o…

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What does patent US8952147B2 cover?
Provided herein are cryptophycin conjugates and compositions containing them. Methods of making and using such compounds also are provided.
Who is the assignee on this patent?
Bouchard Hervé, Brun Marie-Priscille, Commercon Alain, and 2 more
What technology area does this patent fall under?
Primary CPC classification C07D273/08. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).