Substituted xanthine derivatives

US8952016B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8952016-B2
Application numberUS-87404910-A
CountryUS
Kind codeB2
Filing dateSep 1, 2010
Priority dateFeb 27, 2009
Publication dateFeb 10, 2015
Grant dateFeb 10, 2015

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention relates to novel substituted xanthine derivatives that are derivatives of pentoxifylline. The compound of the invention are represented by one of the following structural formulas: The variables for these structural formulas are described herein. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions for which pentoxifylline and related compounds are beneficial.

First claim

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What is claimed is: 1. A compound of Formula C: or a pharmaceutically acceptable salt thereof, wherein R 1 is selected from —CH 3 and —CD 3 ; R 5 is hydrogen or deuterium; and Y is fluorine, wherein the compound has at least 50.1% deuterium incorporation at each position designated as deuterium. 2. The compound of claim 1 , wherein R 1 is —CH 3…

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What does patent US8952016B2 cover?
This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention relates to novel substituted xanthine derivatives that are derivatives of pentoxifylline. The compound of the invention are represented by one of the following structural formulas: The variables for these struct…
Who is the assignee on this patent?
Tung Roger D, Liu Julie F, Harbeson Scott L, and 1 more
What technology area does this patent fall under?
Primary CPC classification C07D473/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).