N-linked glycan compounds
US-9221898-B2 · Dec 29, 2015 · US
US8951990B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8951990-B2 |
| Application number | US-201313735124-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 7, 2013 |
| Priority date | Apr 4, 2008 |
| Publication date | Feb 10, 2015 |
| Grant date | Feb 10, 2015 |
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Described herein are methods for treating a dental disorder in a subject comprising administering to the subject an effective amount of a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue is substituted with a C 1 -C 10 unsubstituted alkyl group or fluoroalkyl group.
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What is claimed: 1. A method for treating inflammation caused by a dental disorder or aphthous ulcer in a subject comprising administering to the subject an effective amount of a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said modified hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue substituted with a C 1 -C 10 u…
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