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Active cores of peptide triazole HIV-1 entry inhibitors
US8951963B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8951963-B2 |
| Application number | US-201313851491-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 27, 2013 |
| Priority date | Jun 24, 2009 |
| Publication date | Feb 10, 2015 |
| Grant date | Feb 10, 2015 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The invention provides a peptide triazole conjugate and derivatives thereof, and methods of its use. The invention also provides an antibody to the peptide triazole conjugate. The invention further provides a method of identifying an HIV-1 entry inhibitor candidate.
First claim
Opening claim text (preview).
What is claimed is: 1. A composition comprising a peptide triazole conjugate comprising a peptide component, wherein the peptide component consists essentially of the sequence X 1 X 2 X 3 NIPWX 4 (SEQ ID No. 3), wherein: the sequence X 1 X 2 X 3 NIPWX 4 is selected from the group consisting of SEQ ID No. 7 (RINNIPW), SEQ ID No. 13 (INNIPW), SEQ ID No. 14 (NNIPWS), SEQ ID No. 15 (INIPWS) and SEQ ID No. 21 (NNIPW); the proline in SEQ ID No. 3 is modified according to Formula I:…
Assignees
Inventors
Classifications
- A61K38/08Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
Physics · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8951963B2 cover?
- The invention provides a peptide triazole conjugate and derivatives thereof, and methods of its use. The invention also provides an antibody to the peptide triazole conjugate. The invention further provides a method of identifying an HIV-1 entry inhibitor candidate.
- Who is the assignee on this patent?
- Philadelphia Health & Educatio, Univ Drexel
- What technology area does this patent fall under?
- Primary CPC classification A61K38/08. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).