Devices and methods for microreactor fluid distribution

Patent metadata

Field	Value
Publication number	US-8951485-B2
Application number	US-62371209-A
Country	US
Kind code	B2
Filing date	Nov 23, 2009
Priority date	Nov 28, 2008
Publication date	Feb 10, 2015
Grant date	Feb 10, 2015

Abstract

A microreactor includes a plurality of interconnected microstructures arranged in m process units with the process units configured to be operable together in parallel. Each of the m process units has a number n of respective process fluid inlets, wherein a number y of the n respective process fluid inlets are connected individually to respective non-manifolded fluid pumps, and wherein a number n minus y of the n respective process fluid inlets are connected to a respective manifolded fluid pump via a manifold, wherein y is an integer from 1 to n−1 inclusive.

First claim

What is claimed is:

1. A microreactor comprising:
a plurality of microstructures fluidically interconnected within process units,
one or more manifolds, and
a plurality of fluid pumps,
said microstructures each being microfluidic devices having internal passages with a characteristic cross-sectional dimension in the few-millimeter to sub-millimeter range, said microstructures further each having a process fluid path and being fluidically interconnected to form a plural number m of process units, said process units each being an interconnected network of microstructures arranged to as to be capable of performing a desired reaction or process along a single primary path along or through the microstructures, said process units further being fluidically interconnected in parallel, each of the m process units having a plural number n of respective process fluid inlets, wherein a number y of the n respective process fluid inlets of each process unit m are connected individually to respective first fluid pumps of the plurality of fluid pumps, and wherein a number n−y of the n respective process fluid inlets are connected to a respective second fluid pump of the plurality of fluid pumps via a respective manifold, wherein y is an integer from 1 to n−1 inclusive, and further wherein a flow resistance, from the respective second fluid pump along the manifold to one of the number n−y of the n respective process fluid inlets is smaller than a flow resistance of a process fluid path through a microstructure fluidically connected to the one of the number n−y of the n respective process fluid inlets.

2. The microreactor according to claim 1 , wherein the microreactor comprises at least one thermal control fluid pump and a thermal control fluid manifold, the thermal control fluid pump being connected via the thermal control fluid manifold to two or more of the plurality of interconnected microstructures.

3. The microreactor according to claim 2 wherein the two or more of the plurality of interconnected microstructures include a thermal control fluid outlet hole having a diameter in the range of 1 to 10 mm.

4. The microreactor according to claim 3 wherein the two or more of the plurality of interconnected microstructures include a thermal control fluid outlet hole having a diameter in the range of 2 to 5 mm.

5. The microreactor according to claim 3 wherein the two or more of the plurality of interconnected microstructures include a thermal control fluid inlet hole having a diameter in the range of 3 to 5 mm.

6. The microreactor according to claim 1 wherein the microstructures comprise at least one of glass, ceramic, and glass ceramic.

7. The microreactor according to claim 1 wherein the microstructures include at least one multilayer microfluidic device.

8. The microreactor according to claim 1 wherein the microstructures include at least one honeycomb-body based microfluidic device.

9. The microreactor according to claim 1 wherein y is 2.

10. The microreactor according to claim 1 wherein y is 1.

11. The microreactor according to claim 1 wherein the respective process units each have a head end at which process fluid flows begin and wherein at least one process fluid inlet of the number y of the n respective process fluid inlets individually connected to the respective first fluid pumps is positioned at a head end of a process unit.

12. The microreactor according to claim 1 wherein the respective process units each have a head end at which process fluid flows begin and wherein at least one process fluid inlet of the number y of the n respective process fluid inlets individually connected to the respective first fluid pumps is not positioned at a head end of a process unit.

13. The microreactor according to any of claim 1 further comprising one or more flow meters for monitoring flow rates in the outputs of a respective manifolded fluid pump.

14. A method of tuning the flow balance of a microreactor comprising the steps of:
providing a microreactor according to claim 1 , the microreactor further comprising one or more flow meters and one or more manual valves;
monitoring the one or more flow meters; and
adjusting the one or more manual valves to tune the flow balance of the microreactor.

Assignees

• Chivilikhin Mikhail Sergeevich
• Gremetz Sylvain Maxime F
• Guidat Roland
• Lavric Elena Daniela
• Lobet Olivier
• Woehl Pierre
• Corning Inc

Inventors

• Chivilikhin Mikhail Sergeevich
• Gremetz Sylvain Maxime F
• Guidat Roland
• Lavric Elena Daniela
• Lobet Olivier
• Woehl Pierre

Classifications

• B01J2219/00831

  Glass · CPC title

• B01J2219/00869

  Microreactors placed in parallel, on the same or on different supports · CPC title

• B01J2219/00783

  Laminate assemblies, i.e. the reactor comprising a stack of plates · CPC title

• B01F13/0059

  Operations & Transport · mapped topic

• B01J2219/00959

  Flow · CPC title