Isolation of dialkylene phenolic glycol ether
US-2024376034-A1 · Nov 14, 2024 · US
US8946483B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8946483-B2 |
| Application number | US-201214131442-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 20, 2012 |
| Priority date | Jul 21, 2011 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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The present invention relates to a method of obtaining radiopharmaceutical precursors, and in particular precursors to protected amino acid derivatives, which are used as precursors for production of radiolabelled amino acids for use in in vivo imaging procedures, such as positron emission tomography (PET).
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What is claimed is: 1. A method for substantially removing a 1,2-dihalogen impurity from a product mixture comprising: (a) reacting the product mixture with an alkoxide, thereby transforming the 1,2-dihalogen impurity into an alkene; and (b) removing the alkene. 2. The method of claim 1 , wherein the alkoxide is methoxide. 3. The method of claim 1 , wherein said methoxide is sodium methoxide. 4. The method of claim…
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