Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents
US-9216970-B2 · Dec 22, 2015 · US
Polymorphs of an active pharmaceutical ingredient
US8946441B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8946441-B2 |
| Application number | US-201113702077-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 24, 2011 |
| Priority date | Jun 25, 2010 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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Abstract
Official abstract text for this publication.
The present invention relates to crystalline form I of Febuxostat as well as to pharmaceutical compositions comprising crystalline form I as an active pharmaceutical ingredient. Furthermore the present invention relates to a further polymorphic form of Febuxostat designated as form II and to a novel solvate of Febuxostat. The present invention also relates to methods of making crystalline form I, form II and the novel solvate of Febuxostat.
First claim
Opening claim text (preview).
The invention claimed is: 1. A crystalline Form I of Febuxostat having an X-ray powder diffraction pattern as measured using CuKα radiation comprising peaks at 2-theta angles of 6.6±0.2°, 12.8±0.2°, 24.5±0.2, 25.8±0.2°, 26.6±0.2°, and being characterized by an IR spectrum comprising absorption bands at wavenumbers of about 2960±2 cm −1 , 2874±2 cm −1 , 2535±2 cm −1 , 2229±2 cm −1 , 1673±2 cm −1 , 1605±2 cm −1 , 1509±2 cm −1 , 1422±2 cm −1 , 1368±2 cm −1 , 1323±2 cm −1 , 1274±2 cm…
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Human Necessities · mapped topic
- C07D277/56Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US8946441B2 cover?
- The present invention relates to crystalline form I of Febuxostat as well as to pharmaceutical compositions comprising crystalline form I as an active pharmaceutical ingredient. Furthermore the present invention relates to a further polymorphic form of Febuxostat designated as form II and to a novel solvate of Febuxostat. The present invention also relates to methods of making crystalline form …
- Who is the assignee on this patent?
- Hotter Andreas, Griesser Ulrich, Adamer Verena, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification C07D277/56. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).