Clonidine formulation in a polyorthoester carrier
US-2015374665-A1 · Dec 31, 2015 · US
Clonidine formulations in a biodegradable polymer carrier
US8946277B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8946277-B2 |
| Application number | US-42019709-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 8, 2009 |
| Priority date | Apr 18, 2008 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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Abstract
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Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of clonidine at or near a target site, one can relieve pain caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discogenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.
First claim
Opening claim text (preview).
What is claimed is: 1. An implantable drug depot for reducing or treating pain in a patient in need of such treatment, the implantable drug depot comprising clonidine in an amount from about 1 wt. % to about 15 wt. % of the drug depot, and a biodegradable polymer, wherein the drug depot has a surface that releases a burst dose of clonidine in an amount of from about 5% to about 20% by weight based on the total weight of clonidine in the depot within 24 hours and an effective amount…
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Human Necessities · mapped topic
Human Necessities · mapped topic
- A61K31/4168Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
- A61K31/4162Primary
Human Necessities · mapped topic
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- What does patent US8946277B2 cover?
- Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of clonidine at or near a target site, one can relieve pain caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discogenic back pain and joint pain, as well as pain that is incidental to surgery. When appr…
- Who is the assignee on this patent?
- Zanella John Myers, Hobot Christopher M, Biggs Danielle L, and 6 more
- What technology area does this patent fall under?
- Primary CPC classification A61K31/4168. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).