2,6,7 substituted purines as hdm2 inhibitors
US-2015368247-A1 · Dec 24, 2015 · US
2′-fluoro-6′methylene carbocyclic nucleosides and methods of treating viral infections
US8946244B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8946244-B2 |
| Application number | US-201013510090-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 16, 2010 |
| Priority date | Nov 16, 2009 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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Abstract
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The present invention relates to 2′-Fluoro-6′-methylene carbocyclic nucleosides, pharmaceutical compositions containing these nucleosides and their use in the treatment or prophylaxis of a number of viral infections and secondary disease states and conditions thereof, especially including Hepatitis B virus (HBV) and secondary disease states and conditions thereof (cirrhosis and liver cancer), Hepatitis C virus (HCV), Herpes Simplex virus I and II (HSV-1 and HSV-2), cytomegalovirus (CMV), Varicella-Zoster Virus (VZV) and Epstein Barr virus (EBV) and secondary cancers which occur thereof (lymphoma, nasopharyngeal cancer, including drug resistant (especially including lamivudine and/or adefovir resistant) and other mutant forms of these viruses.
First claim
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The invention claimed is: 1. A nucleoside compound according to the structure: Where B is Wherein R is H, F, Cl, Br, I, C 1 -C 4 alkyl, —C≡N, —C≡C—R a ,…
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- What does patent US8946244B2 cover?
- The present invention relates to 2′-Fluoro-6′-methylene carbocyclic nucleosides, pharmaceutical compositions containing these nucleosides and their use in the treatment or prophylaxis of a number of viral infections and secondary disease states and conditions thereof, especially including Hepatitis B virus (HBV) and secondary disease states and conditions thereof (cirrhosis and liver cancer), H…
- Who is the assignee on this patent?
- Chu Chung K, Wang Jianing, Univ Georgia
- What technology area does this patent fall under?
- Primary CPC classification C07D473/34. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).