Deuterated compounds
US-2024270731-A1 · Aug 15, 2024 · US
P2X3, receptor antagonists for treatment of pain
US8946231B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8946231-B2 |
| Application number | US-201013259087-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 15, 2010 |
| Priority date | Mar 23, 2009 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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Abstract
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The subject invention relates to novel P2X 3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X 3 receptor subunit modulator.
First claim
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What is claimed: 1. A compound represented by structural formula II: or pharmaceutically acceptable salts and individual enantiomers and diastereomers thereof wherein: A is CH or N; R b is C 1-6 alkyl, or halogen; R 2 represents H, C 1-6 alkyl, CF 3 , OH; R 3 represents (CHR 2 ) n C 5-10 heterocycle,said heterocyclyl substituted with 1 to 3 groups of R a , w…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US8946231B2 cover?
- The subject invention relates to novel P2X 3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X 3 receptor subunit modulator.
- Who is the assignee on this patent?
- Burgey Christopher S, Potteiger Craig M, Merck Sharp & Dohme
- What technology area does this patent fall under?
- Primary CPC classification C07D413/12. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).