Liquid chromatography-mass spectrometry methods for multiplexed detection and quantitation of free amino acids

US8945933B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8945933-B2
Application numberUS-90290810-A
CountryUS
Kind codeB2
Filing dateOct 12, 2010
Priority dateOct 12, 2009
Publication dateFeb 3, 2015
Grant dateFeb 3, 2015

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Abstract

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The present invention provides liquid chromatography-mass spectrometry methods and kits for the specific, sensitive and rapid detection as well as quantitation of free amino acids in samples following High Pressure Liquid Chromatography (HPLC) separation.

First claim

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What is claimed is: 1. A method of analyzing a sample suspected of containing free amino acids using liquid chromatography-mass spectrometry, comprising: preparing a sample to obtain free amino acids; separating the free amino acids by liquid chromatography using a series of at least two chromatographic columns including (a) a first chromatographic column including a graphitic carbon packing material to separate negatively-charged interferents from the free amino acids, followed…

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What does patent US8945933B2 cover?
The present invention provides liquid chromatography-mass spectrometry methods and kits for the specific, sensitive and rapid detection as well as quantitation of free amino acids in samples following High Pressure Liquid Chromatography (HPLC) separation.
Who is the assignee on this patent?
Le Anthony, Cowan Tina, Univ Leland Stanford Junior
What technology area does this patent fall under?
Primary CPC classification G01N33/6806. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).