Polymers for delivering molecules of interest

US8945927B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8945927-B2
Application numberUS-201113637412-A
CountryUS
Kind codeB2
Filing dateMar 29, 2011
Priority dateMar 29, 2010
Publication dateFeb 3, 2015
Grant dateFeb 3, 2015

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to a new class of cationic polymers that self-assemble with a pH-sensitive dissolution switch, and their uses to deliver molecules of interest to a cell. The present invention also relates to compositions comprising said cationic polymers non-covalently associated with a molecule of interest, in particular with a siRNA.

First claim

Opening claim text (preview).

The invention claimed is: 1. A polyethylenimine having multiple amine functions modified or substituted by a radical X, wherein X is C(═Z)—R 1 wherein Z is S or O; and R1 is selected from the group consisting of: and optionally a combination thereof wherein r is an integer from 0 to 2, R is independently selected from the group consisting of H, OH, OCH 3 ,…

Assignees

Inventors

Classifications

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • A61K47/34Primary

    Human Necessities · mapped topic

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Frequently asked questions

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What does patent US8945927B2 cover?
The present invention relates to a new class of cationic polymers that self-assemble with a pH-sensitive dissolution switch, and their uses to deliver molecules of interest to a cell. The present invention also relates to compositions comprising said cationic polymers non-covalently associated with a molecule of interest, in particular with a siRNA.
Who is the assignee on this patent?
Zuber Guy, Frisch Benoit, Creusat Gaelle, and 3 more
What technology area does this patent fall under?
Primary CPC classification C08G73/0206. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).