Gene therapy for tuberous sclerosis
US-2024343768-A1 · Oct 17, 2024 · US
Expanding the eukaryotic genetic code
US8945926B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8945926-B2 |
| Application number | US-201113329202-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 16, 2011 |
| Priority date | Apr 17, 2003 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
First claim
Opening claim text (preview).
What is claimed is: 1. A mammalian cell comprising an orthogonal tRNA (O-tRNA), wherein the O-tRNA comprises a polynucleotide sequence as set forth in SEQ ID NO.: 65, or a cellularly processed form thereof. 2. The cell of claim 1 , wherein the O-tRNA is post-transcriptionally modified. 3. A nucleic acid that encodes an O-tRNA of claim 1 , or a complementary polynucleotide thereof. 4. The nucleic acid of claim 3 , wherei…
Assignees
Inventors
Classifications
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- A61K38/1709Primary
Human Necessities · mapped topic
- C12N15/81Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Patent family
Related publications grouped by family.
External sources
Next steps
Free tools are coming soon. Tell us what you want to track and we'll notify you.
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US8945926B2 cover?
- This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic c…
- Who is the assignee on this patent?
- Chin Jason W, Cropp T Ashton, Anderson J Christopher, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification A61K38/1709. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).