Methods and cellular structures
US-2024209323-A1 · Jun 27, 2024 · US
Medium comprising transforming growth factor β1 and basic fibroblast growth factor
US8945925B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8945925-B2 |
| Application number | US-201314058347-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 21, 2013 |
| Priority date | Dec 16, 2002 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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Abstract
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The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
First claim
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What is claimed is: 1. A culture medium which comprises transforming growth factor β 1 (TGFβ 1 ), and basic fibroblast growth factor (bFGF), wherein the culture medium is free of animal- and/or feeder cells contaminants, and said culture medium is capable of maintaining pluripotent stem cell in an undifferentiated state for at least 5 passages. 2. The culture medium of claim 1 , further comprises serum replacement. 3. The culture medium of…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US8945925B2 cover?
- The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
- Who is the assignee on this patent?
- Technion Res & Dev Foundation
- What technology area does this patent fall under?
- Primary CPC classification C12N5/0607. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).