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Recombinant host cell with deficiency in non-ribosomal peptide synthase production
US8945898B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8945898-B2 |
| Application number | US-201113806128-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 1, 2011 |
| Priority date | Jul 1, 2010 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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Abstract
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The present invention relates to a method for the production of a compound of interest by microbial fermentation, wherein the microbial host cell used has been modified in its genome such that it results in a deficiency in the production of at least one non-ribosomal peptide synthase. The present invention further relates to a microbial host cell that has been modified in its genome such that it results in a deficiency in the production of at least one non-ribosomal peptide synthase. The invention further relates to a compound of interest.
First claim
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The invention claimed is: 1. A method for production of a compound of interest by microbial fermentation comprising: a. providing a microbial host cell, b. culturing said microbial host cell in a culture medium under conditions conducive to expression of the compound of interest, and c. isolating the compound of interest from the culture medium, wherein said microbial host cell has been modified in the genome thereof resulting in a deficiency in production of at least one no…
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- What does patent US8945898B2 cover?
- The present invention relates to a method for the production of a compound of interest by microbial fermentation, wherein the microbial host cell used has been modified in its genome such that it results in a deficiency in the production of at least one non-ribosomal peptide synthase. The present invention further relates to a microbial host cell that has been modified in its genome such that i…
- Who is the assignee on this patent?
- Van Peij Noel Nicolaas Maria Elisabeth, Hans Marcus, Beishuizen Martina, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C12P21/02. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).