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Materials and methods for conjugating a water soluble fatty acid derivative to a protein
US8945897B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8945897-B2 |
| Application number | US-201113329002-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 16, 2011 |
| Priority date | Jul 26, 2010 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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Abstract
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The invention relates to materials and methods of conjugating a water soluble fatty acid derivative to a therapeutic protein comprising contacting the therapeutic protein with an activated water soluble fatty acid derivative under conditions that allow conjugation.
First claim
Opening claim text (preview).
The invention claimed is: 1. A water soluble fatty acid derivative comprising a fatty acid or fatty acid ester attached to a water soluble linker, said fatty acid derivative stably attached to a therapeutic protein, wherein the water soluble linker comprises a water soluble polymer, at least one first functional group attached to the therapeutic protein, wherein the first functional group is an aminooxy group, and a second functional group attached to the fatty acid or fatty acid e…
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Classifications
Human Necessities · mapped topic
Human Necessities · mapped topic
- A61K47/542Primary
Human Necessities · mapped topic
- A61K47/50Primary
Human Necessities · mapped topic
- A61K47/60Primary
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US8945897B2 cover?
- The invention relates to materials and methods of conjugating a water soluble fatty acid derivative to a therapeutic protein comprising contacting the therapeutic protein with an activated water soluble fatty acid derivative under conditions that allow conjugation.
- Who is the assignee on this patent?
- Siekmann Juergen, Sheinecker Richard, Rottensteiner Hanspeter, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification A61K47/542. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).