Method for diagnosing esophageal cancer

US8945849B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8945849-B2
Application numberUS-99379209-A
CountryUS
Kind codeB2
Filing dateMay 21, 2009
Priority dateMay 21, 2008
Publication dateFeb 3, 2015
Grant dateFeb 3, 2015

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Abstract

Official abstract text for this publication.

This invention relates to a composition, kit, or DNA chip for use in diagnosis of esophageal cancer, which comprises a plurality of polynucleotides selected from the group consisting of polynucleotides whose expression levels are varied in esophageal cancer tissues obtained from esophageal cancer patients when compared with cancer-free esophageal tissues obtained from esophageal cancer patients, mutants thereof, and fragments thereof, and to a method for detecting esophageal cancer using the composition, kit, or DNA chip.

First claim

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The invention claimed is: 1. A method for determining whether a human subject has an increased likelihood of having esophageal cancer, comprising: (1) obtaining a test sample of esophageal tissue, or peripheral lymph nodes or another organ suspected of metastasis from esophageal cancer cells, from the subject; (2) selecting a set of the EYA2, SERF1A and IGHG1 genes; (3) assaying the expression level of EYA2, SERF1A, and IGHG1 genes in the test sample obtained from the subject…

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What does patent US8945849B2 cover?
This invention relates to a composition, kit, or DNA chip for use in diagnosis of esophageal cancer, which comprises a plurality of polynucleotides selected from the group consisting of polynucleotides whose expression levels are varied in esophageal cancer tissues obtained from esophageal cancer patients when compared with cancer-free esophageal tissues obtained from esophageal cancer patients…
Who is the assignee on this patent?
Myomoto Akira, Kozono Satoko, Akiyama Hideo, and 5 more
What technology area does this patent fall under?
Primary CPC classification C12Q1/6886. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).