Methods for Nucleic Acid Cleavage
US-2024417778-A1 · Dec 19, 2024 · US
Methods for the selection of aptamers
US8945840B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8945840-B2 |
| Application number | US-91677606-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 16, 2006 |
| Priority date | Jun 10, 2005 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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- Title
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Abstract
Official abstract text for this publication.
The present invention generally relates to methods for selecting aptamers. More specifically, the invention provides methods for the selection of at least one aptamer for use in combination with another epitope binding agent such as another aptamer, an antibody, or a double stranded nucleic acid. The invention also encompasses methods for simultaneously selecting at least two aptamers that each recognize distinct epitopes on a target molecule.
First claim
Opening claim text (preview).
What is claimed is: 1. A method for simultaneously selecting at least two aptamers from a plurality of oligonucleotides of unknown binding specificity, wherein the at least two aptamers comprise a first aptamer sequence and a second aptamer sequence, wherein the first aptamer sequence binds to a first epitope on a target molecule and the second aptamer sequence binds to a second epitope on the target molecule; the method comprising: (a) synthesizing a plurality of first nucleic ac…
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Classifications
Chemistry & Metallurgy · mapped topic
- C12Q1/6811Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12Q1/6804Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8945840B2 cover?
- The present invention generally relates to methods for selecting aptamers. More specifically, the invention provides methods for the selection of at least one aptamer for use in combination with another epitope binding agent such as another aptamer, an antibody, or a double stranded nucleic acid. The invention also encompasses methods for simultaneously selecting at least two aptamers that each…
- Who is the assignee on this patent?
- Heyduk Tomasz, Heyduk Ewa, Univ Saint Louis
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6811. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).