Method of identifying fetal antigens or cell surface markers using phage display technology

US8945828B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8945828-B2
Application numberUS-201113169922-A
CountryUS
Kind codeB2
Filing dateJun 27, 2011
Priority dateDec 8, 2005
Publication dateFeb 3, 2015
Grant dateFeb 3, 2015

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  2. Abstract

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Abstract

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The present application relates to methods for identification of foetal cells and generation and isolation of binding members recognizing foetal cells. The methods of the invention may further be used for other purposes relating to characterization of biological samples and biological antigens. The methods are characterized by the applicability in situations where the interesting objects are present in a limited amount, or where the interesting objects are intermixed with other material, thus the methods are suitable for use in situations where the ratio of the interesting material compared to other material is low.

First claim

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The invention claimed is: 1. A method of isolating binding members recognizing an antigen of a target cell of limited availability in a heterogeneous mixture of target cells and non-target cells comprising the steps: a. identifying the target cells, b. contacting said target cells with a binding member generating system that allows linkage between the genotype and the phenotype of the binding member and is selected from the group consisting of: ribosome display, DNA display, yea…

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What does patent US8945828B2 cover?
The present application relates to methods for identification of foetal cells and generation and isolation of binding members recognizing foetal cells. The methods of the invention may further be used for other purposes relating to characterization of biological samples and biological antigens. The methods are characterized by the applicability in situations where the interesting objects are pr…
Who is the assignee on this patent?
Kolvraa Sten, Christensen Britta, Schelde Palle, and 3 more
What technology area does this patent fall under?
Primary CPC classification C12Q1/6879. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).