Combinations Comprising a Fungicidal Strain and an Active Compound
US-2017318816-A1 · Nov 9, 2017 · US
Medical devices incorporating ceragenin-containing composites
US8945217B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8945217-B2 |
| Application number | US-201213594612-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 24, 2012 |
| Priority date | Aug 25, 2011 |
| Publication date | Feb 3, 2015 |
| Grant date | Feb 3, 2015 |
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Abstract
Official abstract text for this publication.
A medical device that includes a coating of a composite material that includes a polymeric material having a void structure and particulate ceragenin material (i.e., ceragenin particles) associated with the void structure. The average particle size of the ceragenin particles in the composite is in a range from 5 nm to 20 μm, 50 nm to 10 μm, 100 nm to 5 Ξm, or 1 μm to 10 μm. The composite has a high loading of ceragenin particles (e.g., about 10% to about 25%, by weight). The composite has good polymer stability, the ability to release ceragenins from the ceragenin particles disposed in the composite over a sustained period of time at a characteristic elution rate, and the ability to kill large numbers of bacteria and other susceptible microbes over the sustained period of time.
First claim
Opening claim text (preview).
What is claimed is: 1. A medical device, comprising an implantable body; and a composite coated on at least a portion of the implantable body, the composite comprising a polymeric material having ceragenin particles comprised of at least one type of ceragenin compound dispersed therein, wherein the ceragenin particles each comprise a cluster of ceragenin molecules, wherein the ceragenin particles are disposed in a void structure in the polymeric material, wherein the cerage…
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- A01N45/00Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US8945217B2 cover?
- A medical device that includes a coating of a composite material that includes a polymeric material having a void structure and particulate ceragenin material (i.e., ceragenin particles) associated with the void structure. The average particle size of the ceragenin particles in the composite is in a range from 5 nm to 20 μm, 50 nm to 10 μm, 100 nm to 5 Ξm, or 1 μm to 10 μm. The composite has a …
- Who is the assignee on this patent?
- Savage Paul B, Bloebaum Roy D, Williams Dustin L, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification A01N45/00. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).