Sirtuin modulating compounds and applications thereof
US-2024228431-A1 · Jul 11, 2024 · US
US8940918B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940918-B2 |
| Application number | US-201013515239-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 10, 2010 |
| Priority date | Dec 10, 2009 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer's disease and other related amyloid-based neurodegenerative diseases.
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What is claimed is: 1. A compound having the structure of Formula (I), wherein EDG is an electron donor group; πCE is a pi-conjugation element; and WSG is a water soluble group; wherein said electron donor group is R 1 -substituted or unsubstituted alkyl, R 1 -substituted or unsubstituted cycloalkyl, R 1 -substituted or unsubstituted heterocycloalkyl, R 1 -sub…
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