Hiv replication inhibitor
US-2018362543-A1 · Dec 20, 2018 · US
US8940889B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940889-B2 |
| Application number | US-201414202793-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 10, 2014 |
| Priority date | Aug 21, 2009 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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A process for producing a compound represented by formula (1), wherein each of R 1 , R 2 , R 3 and R 4 , which may be the same or different, represents a hydrogen atom or a lower alkyl group, the process includes deprotecting a protective group (R 5 ) of a compound represented by formula (2), wherein R 1 , R 2 , R 3 and R 4 are as defined above, and R 5 represents a protective group of a hydroxy group. The process is an industrially advantageous, simple, and efficient process for producing a key intermediate of a benzo[b][1,4]diazepine-2,4-dione compound, which is a therapeutic medicine for arrhythmia.
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The invention claimed is: 1. A compound represented by formula (2), wherein each of R 1 , R 2 , R 3 and R 4 , which may be the same or different, represents a hydrogen atom or a lower alkyl group, and R 5 is a benzyl group that may be substituted by a group selected from the group consisting of a lower alkyl group, a halogen atom, a cyano group, a lower alkoxy group, a nitro…
Chemistry & Metallurgy · mapped topic
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