Method to produce an immunoglobulin preparation with improved yield

US8940877B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8940877-B2
Application numberUS-201213653332-A
CountryUS
Kind codeB2
Filing dateOct 16, 2012
Priority dateMay 26, 2010
Publication dateJan 27, 2015
Grant dateJan 27, 2015

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  2. Abstract

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Abstract

Official abstract text for this publication.

The present invention provides improved methods for the manufacturing of IVIG products. These methods offer various advantages such as reduced loss of IgG during purification and improved quality of final products. In other aspects, the present invention provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, and/or intramuscular administration. In yet other embodiments, the present invention provides methods of treating a disease or condition comprising administration of an IgG composition provided herein.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for preparing an enriched IgG composition from plasma, the method comprising the steps of: (a) precipitating a cryo-poor plasma fraction, in a first precipitation step, with from about 6% to about 10% alcohol at a pH of from about 7.0 to about 7.5 to obtain a first precipitate and a first supernatant; (b) precipitating IgG from the first supernatant, in a second precipitation step, with from about 23% to about 27% alcohol at a pH of from about 6.7…

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What does patent US8940877B2 cover?
The present invention provides improved methods for the manufacturing of IVIG products. These methods offer various advantages such as reduced loss of IgG during purification and improved quality of final products. In other aspects, the present invention provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, and/or intramuscular administration. In yet other emb…
Who is the assignee on this patent?
Baxter Int, Baxter Healthcare Sa, Baxter Healthcare Sa
What technology area does this patent fall under?
Primary CPC classification A61K39/395. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jan 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).