Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
US8940740B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940740-B2 |
| Application number | US-201113284609-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 28, 2011 |
| Priority date | Oct 28, 2010 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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Certain compounds are provided that can selectively inhibit motile bacteria such as V. cholerae motility. These compounds can indirectly diminish production of cholera toxin and other major virulence required by the cholera bacterium to cause disease.
Opening claim text (preview).
What is claimed is: 1. A method for inhibiting motility of a Vibrio cholerae which comprises contacting the Vibrio cholerae with an effective amount of a compound selected from the group consisting of at least one compound selected from the group consisting of at least one compound represented by the following formulae:…
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