Immunomodulatory Combinations of Antigen and Drug-Lipid Conjugate
US-2024374734-A1 · Nov 14, 2024 · US
Method of treating disease and selectively modulating transcriptional regulation by a glucocorticoid receptor by administering aclacinomycin and dexamethasone
US8940705B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940705-B2 |
| Application number | US-201013143727-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 8, 2010 |
| Priority date | Jan 9, 2009 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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Abstract
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The invention relates to assays to detect selective gene regulation by ligand dependent transcription factors. The invention also relates to selective modulators of the glucocortocoid receptor for treatment of inflammation and allergic and immune-mediated diseases.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of selectively modulating transcriptional regulation by a glucocorticoid receptor, the method comprising the step of: administering to a patient in need thereof, a therapeutically effective amount of aclacinomycin and a glucocorticoid compound, thereby blocking the activation of genes induced by the glucocorticoid compound without inhibiting the repression of genes by the glucocorticoid compound, wherein the glucocorticoid compound is dexamethasone,…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US8940705B2 cover?
- The invention relates to assays to detect selective gene regulation by ligand dependent transcription factors. The invention also relates to selective modulators of the glucocortocoid receptor for treatment of inflammation and allergic and immune-mediated diseases.
- Who is the assignee on this patent?
- Diamond Marc, Gerber Anthony, Univ California
- What technology area does this patent fall under?
- Primary CPC classification A61K31/573. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jan 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).