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Compounds for, and methods of, treating cancer and inhibiting invasion and metastases
US8940701B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940701-B2 |
| Application number | US-201013319476-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 12, 2010 |
| Priority date | May 13, 2009 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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Abstract
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Invasion-inhibiting peptides comprising either a modified cysteine (where the sulfur atom is modified with a alkyl group or other suitable group), and/or b) D-amino acids, for the treatment “cancer” in humans and animals. Such peptides can be used together with other therapies (e.g. radiation) to enhance the therapeutic benefit and reduce invasiveness.
First claim
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The invention claimed is: 1. A composition, comprising a peptide which has an amino acid sequence consisting of PX 1 SX 2 N (SEQ ID NO:5), where X 1 is the D-isomer of histidine, and X 2 is the D-isomer of cysteine, and P, S and N are all L-isomers. 2. The composition of claim 1 , wherein said peptide's amino terminus is blocked with a first group, and said peptide's carboxyl terminus is blocked with a second group, in order to render the peptide more resista…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
- C07K7/06Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US8940701B2 cover?
- Invasion-inhibiting peptides comprising either a modified cysteine (where the sulfur atom is modified with a alkyl group or other suitable group), and/or b) D-amino acids, for the treatment “cancer” in humans and animals. Such peptides can be used together with other therapies (e.g. radiation) to enhance the therapeutic benefit and reduce invasiveness.
- Who is the assignee on this patent?
- Livant Donna, Univ Michigan
- What technology area does this patent fall under?
- Primary CPC classification C07K7/06. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jan 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).