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Cancer diagnosis and treatment of cancer using anti-robo 1 antibody
US8940488B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940488-B2 |
| Application number | US-54753405-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 31, 2005 |
| Priority date | Mar 31, 2004 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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Abstract
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A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for diagnosing cancer comprising the steps of: (a) collecting a test sample selected from blood, serum or plasma from a subject, (b) contacting an anti-ROBO1 antibody which binds to 1-898 of the amino acid sequence of SEQ ID NO: 9 or 1-859 of the amino acid sequence of SEQ ID NO: 11 to the test sample, (c) detecting a first complex comprising the anti-ROBO1 antibody, (d) contacting a control sample selected from blood serum or plasma fro…
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Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
- G01N33/57525Primary
Physics · mapped topic
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Frequently asked questions
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- What does patent US8940488B2 cover?
- A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a …
- Who is the assignee on this patent?
- Aburatani Hiroyuki, Hippo Yoshitaka, Watanabe Akira, and 9 more
- What technology area does this patent fall under?
- Primary CPC classification G01N33/57525. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Jan 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).